572 S Salina Street presents a prime office leasing opportunity for professional or medical
tenants seeking high-visibility space in the heart of Downtown Syracuse. This ±20,943 SF,
two-story building is positioned at the intersection of South Salina Street and West Adams
Street, along the city’s main commercial corridor and near key business, healthcare, and transit
destinations.
Configured for multi-tenant occupancy, the building offers a mix of general office suites and
medical-ready space. The available areas include a lower-level suite of approximately 3,322 SF
and a first-floor suite of approximately 6,575 SF, providing up to 9,897 SF of contiguous space.
The first-floor layout is ideal for legal, financial, consulting, or medical users, and ownership is
open to custom build-out options based on tenant requirements.
Building amenities include a dramatic two-story glass atrium, abundant natural light, access to
approximately 3,000 SF of basement storage, and over 50 dedicated surface parking
spaces—an uncommon amenity for downtown Syracuse. A landscaped courtyard with patio
seating adds additional value for employees and visitors.
The property benefits from excellent visibility and accessibility, fronting South Salina, South
Clinton, and West Adams Streets and located directly across from the Centro Regional Transit
Hub. Tenants enjoy quick access to Interstates 81 and 690, as well as proximity to Syracuse
University, St. Joseph’s Hospital, and Crouse Hospital.
Available Spaces:
● LL – Suite B-1: ±3,322 SF | Office | $16.00/SF NNN
● 1st Floor: ±6,575 SF | Office | $16.00/SF NNN
● Total Contiguous Available: up to ±9,897 SF
Property Facts (Lease Listing):
● Building Size: 20,943 SF
● Floors: 2 + basement storage
● Parking: ±42–50+ surface spaces
● Year Built: 1990
● Zoning: MX-4 Urban Core
● Construction: Steel, wet sprinkler system
Highlights:
● High-visibility downtown corner location
● Flexible, divisible floor plates up to ±9,897 SF
● First-floor suites ideal for professional or medical tenants
● Two-story glass atrium, continuous window lines, and outdoor courtyard
● Basement storage (approx. 3,000 SF) available
● Over 50 surface parking spaces in a downtown environment
● Directly across from Centro Regional Transit Hub; easy access to I-81 and I-690